Force field comparisons
One of the big challenges with simulations of protein dynamics is getting enough data. That’s where Folding@home and all of the compute power that you volunteer to dedicate to running…
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Happy 2026! (belated)
Thanks to everyone who helped get a lot of great science done in 2025! We’re looking forward to a great 2026 with you! First, the good stuff! Folding@home is continuing…
Read moreCatching KRAS in the Act: Simulations Reveal New Paths for Targeted Protein Degradation
Mutations in the KRAS protein are among the most common drivers of human cancers, including lung, pancreatic, and colorectal tumors. Despite decades of effort, KRAS has been considered a particularly…
Read moreQuantifying the accuracy of protein simulation models
How do we know our molecular simulation models are accurate? This is a very important aspect of all the work we perform on Folding@home. If we want to use…
Read moreFAH is enabling AI developments
With all the advances happening in artificial intelligence (AI), it’s natural to ask if one could develop an algorithm that predicts protein dynamics with far less computer time than running…
Read moreReunion in Madison
Last week we had a really nice meeting in Madison, WI on combining simulations and machine learning to understand protein dynamics. This meeting was hosted through CECAM (Centre Européen de…
Read moreExperimental confirmation of spike dynamics
Early during the COVID-19 pandemic, our simulations of the coronavirus spike protein led us to predict that it opens up far more widely than previously thought. This opening reveals ‘cryptic’…
Read moreBRCA1 in breast cancer
About 2,300,000 people are diagnosed with breast cancer every year. Of these, approximately 70,000 have mutations in the breast cancer gene 1 (BRCA1), which encodes the BRCA1 protein. BRCA1 plays…
Read moreStand up for Science
Please join us as we Stand Up for Science in cities across the US on Friday March 7. You can find more details on the main event in Washington DC…
Read moreNew client v8.4.9
If you haven’t already, we invite you to check out the latest release of the Folding@home client (v8.4.9)! This version makes it much easier to create and join teams. You…
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