Rational drug design efforts typically focus on identifying inhibitors that bind to protein active sites. Pockets that are not present in crystallographic structures yet can exert allosteric (i.e., long-range) control…
Read moreRGD peptides (those which contain a conserved Arg-Gly-Asp sequence) can adopt a hairpin loop structure found in integrin-binding proteins such as fibronectin, fibrinogen, and vitronectin. Over the last few decades,…
Read moreHere’s a video on the more technical details of Folding@home: how it works, what we’ve done, where we’re going, etc. It’s a recording of a talk I presented at the…
Read moreAs we have previously announced, the bigadv (BA) program will reach end-of-life on January 31, 2015. We would like to thank all the donors who have contributed to the program. …
Read moreOn Saturday May 30th, 2015, the Huntington’s Disease Society of America SF Celebration of Hope will Honor Prof. Pande for his work with Folding@home. Details are in poster to the…
Read moreI’m happy to announce our participation in the Cancer Systems Biology Scholars (CSBS) program, which provides a unique opportunity for postdoctoral training in cancer systems biology in a dynamic, multi-disciplinary…
Read moreAs part of our recent assignment server upgrades we are rolling out a new psummary page (which lists all of the active Folding@home projects). This new page includes projects which are…
Read moreI’m excited to announce today our new initiative for Folding@home on Android Mobile phones, with a beta version being released today. In collaboration with Sony, we have brought Folding@home to…
Read moreNow we have over 1 millisecond of data for rhodopsin, a key signaling protein in vision. In the new year, we will be running more simulations to get better statistics…
Read moreGiven some known driver issues with recent NVIDIA maxwell chips and Core18 ( https://www.reddit.com/r/foldingathome/ … l_support/ ), we are temporarily restricting our core18 projects (e.g. 1047*) to use pre-maxwell GPUs.…
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