A number of active projects on Folding@home right now aim to understand how different forms of the protein apolipoprotein E (ApoE) determine one’s risk of developing Alzheimer’s disease. Alzheimer’s disease…
Read moreContributed by Justin Miller, Bowman Lab Alzheimer’s disease (AD), a dementia characterized by loss of memory and cognitive abilities, afflicts over an estimated 44 million people worldwide. While recent clinical…
Read moreA new paper from our lab has just been published! We looked at how the brain works at atomic resolution – well, not the whole brain yet, unfortunately, but one…
Read moreRelated Articles Computationally Discovered Potentiating Role of Glycans on NMDA Receptors. Sci Rep. 2017 Apr 05;7:44578 Authors: Sinitskiy AV, Stanley NH, Hackos DH, Hanson JE, Sellers BD, Pande VS Abstract…
Read moreFAH researcher Dr. Diwakar Shukla has continued work on HD. He has new results on the behavior of the HTT protein and will be presenting his results at the Annual…
Read moreWe are continuing our work with AD in terms of repurposing an existing drug against the leads we have found from Folding@home. The benefit of this approach is that this…
Read moreWe’re very excited to report on our progress towards our goal to develop new small molecule drug candidates for AD. In a paper just published in the Journal of Medicinal…
Read moreFAH researcher Dr. Veena Thomas has proposed a novel therapeutic strategy for HD and this proposal looks to be funded by NIH (as of September 22, 2010 still pending). This…
Read moreWe have been working closely with the Nanomedicine Center for Protein Folding on pushing our lead compounds forward. They have gone from the test tube to the first round of…
Read moreOur new paper #62: “The predicted structure of the headpiece of the Huntington protein and its implications for Huntington’s Disease.” just came out in the Journal of Molecular Biology.
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