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Category: Papers

A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization.

October 24, 2019 by Anton Thynell

https://www.ncbi.nlm.nih.gov/pubmed/31577956?dopt=Abstract

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Ancestral reconstruction reveals mechanisms of ERK regulatory evolution.

August 13, 2019 by Anton Thynell

Ancestral reconstruction reveals mechanisms of ERK regulatory evolution. Elife. 2019 Aug 13;8: Authors: Sang D, Pinglay S, Wiewiora RP, Selvan ME, Lou HJ, Chodera JD, Turk BE, Gümüş ZH, Holt…

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Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia.

June 20, 2019 by Anton Thynell

Related Articles Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia. Nat Commun. 2019 Jun 19;10(1):2691 Authors: Minuesa G, Albanese SK, Xie W, Kazansky Y, Worroll D, Chow A,…

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The dynamic conformational landscape of the protein methyltransferase SETD8.

May 13, 2019 by Anton Thynell

The dynamic conformational landscape of the protein methyltransferase SETD8. Elife. 2019 May 13;8: Authors: Chen S, Wiewiora RP, Meng F, Babault N, Ma A, Yu W, Qian K, Hu H,…

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A Site-Specific ImmunoPET Tracer to Image PD-L1.

March 15, 2019 by Anton Thynell

A Site-Specific ImmunoPET Tracer to Image PD-L1. Mol Pharm. 2019 Mar 15;: Authors: Wissler HL, Ehlerding EB, Lyu Z, Zhao Y, Zhang S, Eshraghi A, Buuh ZY, McGuth JC, Guan…

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Cooperative Changes in Solvent Exposure Identify Cryptic Pockets, Switches, and Allosteric Coupling.

February 12, 2019 by Anton Thynell

https://www.ncbi.nlm.nih.gov/pubmed/30744991?dopt=Abstract

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Fluorinated Aromatic Monomers as Building Blocks to Control α-Peptoid Conformation and Structure.

February 11, 2019 by Anton Thynell

https://www.ncbi.nlm.nih.gov/pubmed/30739443?dopt=Abstract

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What Makes a Kinase Promiscuous for Inhibitors?

January 7, 2019 by Anton Thynell

https://www.ncbi.nlm.nih.gov/pubmed/30612951?dopt=Abstract

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Advanced Methods for Accessing Protein Shape-Shifting Present New Therapeutic Opportunities.

December 17, 2018 by Anton Thynell

https://www.ncbi.nlm.nih.gov/pubmed/30555007?dopt=Abstract

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Atomistic structural ensemble refinement reveals non-native structure stabilizes a sub-millisecond folding intermediate of CheY.

November 27, 2018 by Anton Thynell

https://www.ncbi.nlm.nih.gov/pubmed/28272524?dopt=Abstract

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