COVID Moonshot Sprint 10
Sprint 10 aims to help optimize the P1 pocket substituent to work around metabolism issues with our current best lead compounds. We’ve been quiet lately, but that’s because we’ve been…
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Understanding the impact of the lipid bilayer on ion channel function
Contributed by Sergio Perez Conesa All our thoughts, movements, and heartbeats are governed by electrical signals in our bodies. These electrical signals are nothing but charged particles, called ions, crossing…
Read moreMaximizing the impact of Folding@home by engaging industry collaborators
For over 20 years, Folding@home has relied almost exclusively on government agencies like the National Science Foundation (NSF) and National Institutes of Health (NIH) for financial support. We’ve also been…
Read more2020 in review, and happy new year 2021!
TL;DR: During 2020, Folding@home was like the citizens’ fleet in the movie Star Wars: The Rise of Skywalker. Everyone came together to face a common foe, in this case the…
Read moreSARS-CoV-2 Nsp16 activation mechanism and a cryptic pocket with pan-coronavirus antiviral potential
As we all know, coronaviruses are a major threat to human health. In the past two decades these viruses have caused three epidemics: SARS in 2004, MERS in 2012, and…
Read moreUpdate for Those Using Advanced Remote Client Management Configurations
Hello Folders! We’ve been made aware of a potential issue for users who are using certain advanced manual configuration options for remote client management using fah-control. We actively recommend against…
Read moreCOVID Moonshot Sprint 5
Sprint 5 to prioritize compounds for the open science patent-free COVID Moonshot drug discovery project has launched! Rev up your GPUs to help develop a new therapy.
Read moreCould a new class of antibodies treat COVID-19 in a manner that avoids resistance?
Several antibodies are now in clinical trials to both treat and provide protection against COVID-19. But one of these binds in a completely surprising way, and in a manner that may head off viral resistance. How does it work? We’re trying to find out!
Read moreCOVID Moonshot Sprint 4
As the COVID Moonshot continues to make rapid progress, the fourth free energy sprint focused on a backup lead series that suddenly pulls into the lead!
Read moreTogether we are Even More Powerful: GPU folding gets a powerup with NVIDIA CUDA support!
Folding@home adds CUDA support to give NVIDIA GPUs big boosts in speed!
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