mTOR: Projects 10491-10499
In projects 10491-10499, the Chodera lab takes a look at mTOR, a serine/threonine kinase. The MTOR gene was originally discovered in yeast in 1991 and named TOR1/2 because it was…
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Introducing Shukla Group@Illinois
Shukla group (http://www.shuklagroup.org) at University of Illinois at Urbana-Champaign has just configured new Folding@home servers (ds01[a-d].scs.illionis.edu), which would help us carry out exciting computational experiments in collaboration with the vibrant…
Read moreSrc kinase: Project 10471
In Project 10471 we at the Chodera lab are looking at Src kinase. The Src gene was first discovered as responsible for the tumorogenicity of Rous sarcoma virus. This gene…
Read moreFighting cancer on Folding@home: FDA approved kinase inhibitors
You may have noticed a trend in the type of proteins being simulated on Folding@home recently. A number of Folding@home labs are collaborating in an attempt to understand the role…
Read moreNew projects to help design selective inhibitors of protein methyltransferases
The Chodera lab has teamed up with Luo lab at MSKCC to study another important class of cancer targets: protein methyltransferases. These are protein-modifying enzymes that catalyze the transfer of…
Read moreChanges to the bigadv threshold
We have a policy of periodically re-evaluating the bigadv program, including the threshold required to run bigadv projects. It is the intent of bigadv to match large and resource-intensive work…
Read moreIntroducing the Chodera lab at the Memorial Sloan-Kettering Cancer Center
The Chodera laboratory at the Memorial Sloan-Kettering Cancer Center (MSKCC) has just received our new Folding@Home server hardware, allowing us to tap into the 10+ PFLOP/s of computing resources generously provided…
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