Update on network issues
As I've discussed before, we have been having issues with a particular subnet (171.64.122.XX) for Folding@home servers. The symptoms were dropped connections and general challenges returning WUs. We asked for…
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Main AS restarted; back up now, down for the last 20 min
We restarted the main AS. The stats will also skip one cycle due to this, but everything else should be back to normal.
Read moreSide-chain recognition and gating in the ribosome exit tunnel
Paula M. Petrone, Christopher D. Snow, Del Lucent, and Vijay S. Pande Proceedings of the National Academy of Sciences, USA 2008 SUMMARY The ribosome is a fascinating molecular machine, responsible…
Read moreSimulating oligomerization at experimental concentrations and long timescales: A Markov state model approach
Nicholas W. Kelley, V. Vishal, Grant A. Krafft, and Vijay S. Pande J. Chem. Phys. 129, 214707 (2008); DOI:10.1063/1.3010881 SUMMARY. Abeta misfolding and aggregation is believed to be the cause…
Read moreStructural Insight into RNA Hairpin Folding Intermediates
Gregory R. Bowman, Xuhui Huang, Yuan Yao, Jian Sun, Gunnar Carlsson, Leonidas J. Guibas, and Vijay S. Pande J. Am. Chem. Soc., 130 (30), 9676–9678, 2008 ABSTRACT. Hairpins are a…
Read moreConvergence of folding free energy landscapes via application of enhanced sampling methods in a distributed computing environment.
Xuhui Huang,Gregory R. Bowman,and Vijay S. Pande J Chem Phys. 2008 May 28;128(20):205106. ABSTRACT.We have implemented the serial replica exchange method (SREM) and simulated tempering (ST) enhanced sampling algorithms in…
Read moreUpdate on server issues
There have been two issues which have been causing FAH some series issues. I wanted to give an update. First, networking on subnet 171.64.122.XX seems to be very slow and…
Read moreUpdate on the viewer for GPU clients
We've been looking into the issues some people have been finding with the viewer. On the ATI/AMD side, the catalyst 8.9 drivers seem to have resolved a number of issues…
Read moreAlzheimer’s Disease
We presented our results regarding new possible drugs to fight Alzheimer’s Disease at a Stanford University meeting organized by the NIH Roadmap Nanomedicine center.
Read moreViral diseases
During this year we published our first work on some of the molecular interactions that occur during the initial stages of viral infection, and how they can impact current antivirus…
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