Recent talk of results from Folding@home
Donors are often curious to hear about recent results. While one can read our papers, listed on our web site, those are fairly technical and intended for a biological or…
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Equilibrium conformational dynamics in an RNA tetraloop from massively parallel molecular dynamics
AJ DePaul, EJ Thompson, SS Patel, K Haldeman & EJ Sorin. Nucleic Acids Research (2010) 38, 4856-4867 (Featured Cover Article) SUMMARY. We continue to study a small but ubiquitous RNA…
Read moreEvaluating Molecular Mechanical Potentials for Helical Peptides and Proteins.
EJ Thompson, AJ DePaul, SS Patel & EJ Sorin. PLoS ONE (2010) 5, e10056 SUMMARY. Our assessment of biophysical force fields as applied to helical peptides and proteins continues with…
Read moreA simple theory of protein folding kinetics.
V. S. Pande. Physical Review Letters (2010). SUMMARY. Recent work from detailed simulations of protein folding resulting from Folding@home have suggested some surprises and radical changes in how one conceptualizes…
Read moreProtein folded states are kinetic hubs.
G. R. Bowman and V. S. Pande. Proceedings of the National Academy of Sciences, USA (2010). SUMMARY. By analyzing recent results from Folding@home, we have found a set of general…
Read moreAtomic-Resolution Simulations Predict a Transition State for Vesicle Fusion Defined by Contact of a Few Lipid Tails.
P. M. Kasson, E. Lindahl, and V. S. Pande. PLoS Computational Biology 6(6): e1000829 (2010). SUMMARY. Membrane fusion is a common underlying process critical to neurotransmitter release, cellular trafficking, and…
Read moreMolecular Simulation of ab Initio Protein Folding for a Millisecond Folder NTL9(1−39)
Voelz VA, Bowman GR, Beauchamp K, Pande VS. Journal of the American Chemical Society (2010) SUMMARY. Simulating protein folding on the millisecond timescale has been a major challenge for many…
Read moreFolding@home 10th anniversary
It’s with great pleasure that I announce that today is Folding@home’s official tenth anniversary. It’s been an amazing 10 years, especially in terms of what we’ve collectively been able to…
Read moreTen years of folding
We celebrated Folding@home’s 10 year anniversary.
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