Contributed by Justin Miller, Bowman Lab Alzheimer’s disease (AD), a dementia characterized by loss of memory and cognitive abilities, afflicts over an estimated 44 million people worldwide. While recent clinical…
Read more
Sprint 10 aims to help optimize the P1 pocket substituent to work around metabolism issues with our current best lead compounds. We’ve been quiet lately, but that’s because we’ve been…
Read more
Contributed by Sergio Perez Conesa All our thoughts, movements, and heartbeats are governed by electrical signals in our bodies. These electrical signals are nothing but charged particles, called ions, crossing…
Read more
For over 20 years, Folding@home has relied almost exclusively on government agencies like the National Science Foundation (NSF) and National Institutes of Health (NIH) for financial support. We’ve also been…
Read more
TL;DR: During 2020, Folding@home was like the citizens’ fleet in the movie Star Wars: The Rise of Skywalker. Everyone came together to face a common foe, in this case the…
Read more
As we all know, coronaviruses are a major threat to human health. In the past two decades these viruses have caused three epidemics: SARS in 2004, MERS in 2012, and…
Read moreHello Folders! We’ve been made aware of a potential issue for users who are using certain advanced manual configuration options for remote client management using fah-control. We actively recommend against…
Read more
Sprint 5 to prioritize compounds for the open science patent-free COVID Moonshot drug discovery project has launched! Rev up your GPUs to help develop a new therapy.
Read more
Several antibodies are now in clinical trials to both treat and provide protection against COVID-19. But one of these binds in a completely surprising way, and in a manner that may head off viral resistance. How does it work? We’re trying to find out!
Read more
As the COVID Moonshot continues to make rapid progress, the fourth free energy sprint focused on a backup lead series that suddenly pulls into the lead!
Read more