Protein folding under confinement: a role for solvent.
D. Lucent, V. Vishal, V. S. Pande. Proceedings of the National Academy of Sciences (2007) Local PDF SUMMARY: When proteins fold inside a cell, they are frequently subjected to various…
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Automatic discovery of metastable states for the construction of Markov models of macromolecular conformational dynamics.
J. Chodera, N. Singhal, V. S. Pande, K. Dill, and W. Swope. Journal of Chemical Physics, (2007) SUMMARY: In order to break up calculations to run on Folding@home and then…
Read moreStorage@home: Petascale Distributed Storage
Adam L Beberg and Vijay S. Pande. IPDPS (2007) SUMMARY: Storage@home is a distributed storage infrastructure developed to solve the problem of backing up and sharing petabytes of scientific results…
Read moreMeet FAH team member Paula Petrone
Since I’m on the topic of the ribosome, let me talk a bit about another group member working on the ribosome: Paula Petrone. Paula’s background is physics and biophysics. Her…
Read moreScheduled network outage Oct 11 at 5am pacific time
Networking will be upgrading the switches next Thursday 10/11 during their maintenance window between 5am to 6am pacific time. During this period, FAH will experience a network interruption for about…
Read moreMeet FAH team member Relly Brandman
Relly Brandman is a graduate student in the Chemical and Systems Biology Department at Stanford. This department was originally called the Molecular Pharmacology Department and it still has a tradition…
Read moreThe ribosome
We’ve been putting a lot of effort into studying the ribosome. The ribosome is particularly important for proteins — it’s where the messenger RNA (mRNA) is converted into proteins, i.e.…
Read moreWhat causes proteins to fold part 1: hydrophobicity
What causes proteins to fold? This is a complex question, but there are some rules of thumb that have been learned especially for how proteins behave in vitro (eg in…
Read moreHow FAH works: Thermodynamic alchemy
One of the remarkable strengths of thermodynamics is that it is in many ways more general than many of the laws of physics. One of the key concepts in thermodynamics…
Read moreWhat can Thermodynamics tell us?
Thermodynamics (and it’s "older brother" statistical mechanics — but I’ll refer to both as Thermodynamics) plays a very important role in what we do. I thought I’d talk a little…
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