New initiative: FAH on Android

I’m excited to announce today our new initiative for Folding@home on Android Mobile phones, with a beta version being released today.  In collaboration with Sony, we have brought Folding@home to…

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Bowman lab update on vision

Now we have over 1 millisecond of data for rhodopsin, a key signaling protein in vision.  In the new year, we will be running more simulations to get better statistics…

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Surprisal Metrics for Quantifying Perturbed Conformational Dynamics in Markov State Models.

Markov state models (MSMs), which model conformational dynamics as a network of transitions between metastable states, have been increasingly used to model the thermodynamics and kinetics of biomolecules. In considering perturbations to molecular dynamics induced by sequence mutations, chemical modifications, or changes in external conditions, it is important to assess how transition rates change, independent of changes in metastable state definitions. Here, we present a surprisal metric to qu…

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A subreddit for Folding@home donors to discuss topics

At https://www.reddit.com/r/foldingathome, we’ve created a subreddit  dedicated to improving the bi-directional flow of communication between Folding@home donors, researchers, and developers. Although the official community-driven technical support forum is over in…

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