Parkinson’s Disease

We have performed preliminary studies on a key protein implicated in Parkinson’s disease (PD).

Alpha-synuclein is a natively unfolded protein and its folding/misfolding (see figure on the right for misfolded aggregates) appears to be critically linked to PD. We have evaluated the application of various FAH methods to this problem. For now, PD stands still as a pilot project, with the bulk of our efforts going into Alzheimer’s Disease (AD) and Huntington’s Disease (HD).

By Jftrempe (Own work) [CC BY-SA 3.0], via Wikimedia Commons
By Jftrempe (Own work) [CC BY-SA 3.0], via Wikimedia Commons

  • Prof. Vijay Pande presented recent FAH work

    Prof. Vijay Pande presented recent FAH work on AD at the National Parkinson’s Foundation conference.

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  • Pilot study on PD

    We have only done a pilot study on PD and are looking for funding to continue our work in this area.

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