• Understanding epigenetic cancer targets with Folding@home: Histone methyltransferases NSD1, NSD2, and NSD3

    The Chodera Lab at the Memorial Sloan Kettering Cancer Center is now running a series of projects to study the conformational dynamics of histone methyltransferases to aid in the rational design of new small molecule…

    Read more
  • New projects to help design selective inhibitors of protein methyltransferases

    The Chodera lab has teamed up with Luo lab at MSKCC to study another important class of cancer targets: protein methyltransferases. These are protein-modifying enzymes that catalyze the transfer of…

    Read more