Stand up for Science
Please join us as we Stand Up for Science in cities across the US on Friday March 7. You can find more details on the main event in Washington DC…
Read moreCategory: Folding@home Blog
New client v8.4.9
If you haven’t already, we invite you to check out the latest release of the Folding@home client (v8.4.9)! This version makes it much easier to create and join teams. You…
Read moreHappy new year 2025!
Thanks to everyone who participated in Folding@home this past year, and happy new year to you and yours! With your help, we’ve made a lot of progress towards understanding biology…
Read moreAn allosteric glue
There has been growing interest in developing drugs that bind two or more proteins to “glue” them together. Tacrolimus (aka FK506) is a famous example.  Tacrolimus is an immune-suppressant that…
Read morePredicting drugs’ lipophilicity with Folding@home
Computational chemistry and machine learning continue to play an increasing role in drug discovery. One advance has been the increased accuracy with which we can predict the affinity of…
Read moreThe Bowman Lab Rig
Folding@home is an unmatched resource for running molecular dynamics simulations on a massive scale. The need for significant computational resources doesn’t end with data generation though, as analyzing all the…
Read moreImproving protein design on Folding@home
The protein design field has been making great strides with the advent of new machine learning tools trained on large databases of protein structures and sequences. While designs coming from…
Read moreTackling Condensates
In recent years, scientists have identified a new type of compartment in cells, often called a condensate. These condensates form when weakly interacting proteins and RNA molecules segregate themselves from…
Read moreNew software release!
We’re delighted to announce the full release of our new client software! We named this release “Bastet” after the Ancient Egyptian goddess associated with protection from disease. You can download…
Read moreConnecting with single molecule experiments
Our new work shows how to predict the results of single molecule experiments from large simulations, like those performed on Folding@home. Showing that simulations are consistent with experiments is important…
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