When it comes to designing novel drugs, achieving specificity is a major challenge. An effective drug must bind tightly to its target protein while avoiding unwanted side effects that can…
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G proteins are essential molecular players in the intricate symphony of cellular signaling. From our vision to our sense of smell, neurotransmission to cell growth, G proteins are at the…
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This past year, we have largely focused on following through on our commitment to take on SARS-CoV-2. Looking ahead, there’s more work to be done on the pandemic, and we…
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TL;DR: During 2020, Folding@home was like the citizens’ fleet in the movie Star Wars: The Rise of Skywalker. Everyone came together to face a common foe, in this case the…
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To celebrate the 20th anniverary of Foldingathome we are hosting a celebration live stream: When? Wednesday the 18th at Noon – 3:30 PM pacific time Where? Twitch.tv/foldingathomehomedotorg Recorded video: https://www.twitch.tv/videos/807988760…
Read moreWe’re reaching the end of 2015 and as in previous years, I’d like to summarize for donors what Folding@home (FAH) has done in 2015 and where we’re going. In general,…
Read moreIn a new paper, we describe our efforts to use Markov State Models (MSMs) to study the how tryptophan mutations affect the folding and conformational dynamics of a series of…
Read moreA key new work from the Pande Group just came out in Nature Chemistry and got a nice holiday present: our work on the cover! Briefly, we applied methods developed and…
Read moreWe've rolled out the latest version 7.3 client to the main web site. This new client should be much easier to install and comes with a new web interface which…
Read moreHere's a guest post from Jesse Victors, one of the volunteers helping with Folding@home documentation. I am pleased to announce that the Folding@home article on Wikipedia is now a Featured…
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