We assisted Chris Garcia’s lab with their work with Interleukin 2 (IL-2), a protein which assists the immune system in fighting pathogens and cancer tumors. While injecting a patient with…
Read moreWe are simulating many forms of Pin1 WW domain, a protein implicated in some cancers and Alzheimer’s disease. Understanding the role of mutations on misfolding can have important biomedical consequences.
Read moreWe’re studying the folding of ubiquitin, a small regulatory protein found in almost all cells in human body. It is part of a large regulatory system that labels other unneeded…
Read moreAt FAHcon 2012, Dr. Xuhui Huang presented our recent results of the molecular mechanisms of gene transcription. Transcription is the first step in reading genomic DNA, and regulation of this…
Read moreDr. Peter Kasson has been applying his work on viruses to cancer, as many cancers are virus-associated.
Read morePlease see this blog post for Dr. John Chodera’s anti-cancer strategy involving kinases.
Read moreThis video is a year old (and we've previously posted the audio), but looking at this again, a lot is still relevant (and we didn't post the video url), so…
Read moreGuest post from Dr. Gregory Bowman, UC Berkeley Two general objectives of the Folding@home project are (1) to explain the molecular origins of existing experimental data and (2) to provide…
Read moreGuest post from Dr. Gregory Bowman, UC Berkeley We’ve been making a lot of progress with developing Markov state model (MSM) methods for analyzing the data we generate with the…
Read moreGuest post from Dr. Gregory Bowman, UC Berkeley Most rational drug design efforts assume the target protein exists in a single structure and that the structure of one region of…
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