News – Page 34 – Folding@home

Kinetic network models of tryptophan mutations in β-hairpins reveal the importance of non-native interactions.

June 9, 2015 by Anton Thynell

We present an analysis of the most extensive explicit-solvent simulations of β-hairpins to date (9.4 ms in aggregate), with the aim of probing the effects of tryptophan mutations on folding. From molecular simulations of GB1 hairpin, trpzip4, trpzip5, and trpzip6 performed on Folding@home, Markov State Models (MSMs) were constructed using a unified set of metastable states, enabling objective comparison of folding mechanisms. MSM models display quantitative agreement with experimental structur…

Problem with NaCl Client

June 6, 2015 by Vijay Pande

We see that there is an issue with our NaCl Client (at http://nacl.foldingathome.org), with donors seeing this error: Warning: Unexpected response to AS assignment request: error,DB ERROR: IO error: log.leveldb/016519.ldb:…

New Core tech update: OpenMM (GPU) and Gromacs (CPU)

May 29, 2015 by Vijay Pande

We’ve been pushing hard to improve the performance of OpenMM, especially in OpenCL as it’s now used in Folding@home. We’ve got some great news hot off of the presses. These…

Introducing Shukla Group@Illinois

May 26, 2015 by Diwakar Shukla

Shukla group (http://www.shuklagroup.org) at University of Illinois at Urbana-Champaign has just configured new Folding@home servers (ds01[a-d].scs.illionis.edu), which would help us carry out exciting computational experiments in collaboration with the vibrant…

Multi-core CPU jobs

May 21, 2015 by Vijay Pande

We’ve been getting reports that FAH is low on CPU jobs. We’re in the process of adding more multi-core jobs to existing projects. Also, currently lead developer Joseph Coffland’s main…

Issue with foldingathome.org

May 17, 2015 by Vijay Pande

Likely due to a recent extremely heavy (and unusually rare) electrical storm, we’ve had some server issues last week. I thought we’d gotten them all but we see now that…

Issues with 171.67.108.60 and 171.64.65.124

May 9, 2015 by Vijay Pande

We see the issues with 171.67.108.60 and 171.64.65.124 and are looking into it.

Fixes for recent FAH server outage

May 7, 2015 by Vijay Pande

We recently ran into some problems with our assignment server (AS). The AS is responsible for distributing the computational power of Folding@home by sending client’s to different work servers (WS), which in…

Two server issues being worked on

May 7, 2015 by Vijay Pande

We have two server issues being worked on. There were some issues with the main AS and with the server serving SMP WUs (171.64.65.124). We’ll post updates as we have…

New Maxwell WUs

May 5, 2015 by Vijay Pande

A heads up for GPU donors: We’ve been looking into issues with Maxwell GPU project WUs shortages. In addition to adding more WUs, we are also working to improve our…