About protein aggregation-related diseases For newly synthesized proteins to become functional, they have to fold into a particular three-dimensional structure or conformation first. During the folding process, a protein…
Read moreWe (the Bowman lab) have completed our move to Washington University in St Louis and have our new servers up and running. While our primary server won’t be replacing Folding@home…
Read moreOur recent work on understanding how protein misfolding occurs (http://www.cell.com/biophysj/abstract/S0006-3495(14)00722-X) has shed light on the nature of misfolding and potential subsequent aggregation (relevant for protein misfolding disease), demonstrating that misfolded…
Read moreWe’re excited to share some recent results from our lab that combine simulation and experimental structural biology. This has been a wonderful collaboration with my colleague Linda Columbus, a Chemistry…
Read moreRecently, for the first time, Stanford’s Chemistry Department did a look back at research highlights from the last (2013-2014) academic year done in the Department. Folding@home is prominently highlighted: https://chemistry.stanford.edu/events/chemistry-year-review
Read moreOver the weekend, we had an issue with one our key servers that handles the stats update. The sysadmins have taken care of it and the stats update is now…
Read moreIn the past couple of years, Xuhui Huang’s group at HKUST (http://compbio.ust.hk/) has performed large-scale molecular dynamics simulations at Folding@Home (Project 2974-2975) to investigate the mis-folding of the hIAPP (human…
Read moreI’ve been an independent researcher at UC Berkeley for the past three years and have now accepted an Assistant Professorship at Washington University in St Louis. I’ll start the process…
Read moreLast month Professor Pande gave a webinar/Q&A covering Folding@home’s next steps and accomplishments. Click on the link below to listen to and view the presentation- http://on-demand.gputechconf.com/gtc/2014/webinar/gtc-express-folding-at-home-webinar.mp4
Read moreThe Bowman lab is beginning a new effort to understand the molecular mechanisms underlying vision and the origins of inherited forms of blindness. As a starting point, we’ve launched some…
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