Happy new year 2025!
Thanks to everyone who participated in Folding@home this past year, and happy new year to you and yours! With your help, we’ve made a lot of progress towards understanding biology…
Read moreCategory: Folding@Home
The Bowman Lab Rig
Folding@home is an unmatched resource for running molecular dynamics simulations on a massive scale. The need for significant computational resources doesn’t end with data generation though, as analyzing all the…
Read moreImproving protein design on Folding@home
The protein design field has been making great strides with the advent of new machine learning tools trained on large databases of protein structures and sequences. While designs coming from…
Read moreTackling Condensates
In recent years, scientists have identified a new type of compartment in cells, often called a condensate. These condensates form when weakly interacting proteins and RNA molecules segregate themselves from…
Read moreNew software release!
We’re delighted to announce the full release of our new client software! We named this release “Bastet” after the Ancient Egyptian goddess associated with protection from disease. You can download…
Read moreConnecting with single molecule experiments
Our new work shows how to predict the results of single molecule experiments from large simulations, like those performed on Folding@home. Showing that simulations are consistent with experiments is important…
Read moreTowards physics-based precision medicine
The goal of precision medicine is to utilize our knowledge of the molecular causes of disease to better diagnose and treat patients. In the precision medicine framework, diseases are subdivided…
Read moreAlphaFold opens new opportunities for Folding@home
Folding@home has long sought to understand how proteins self-assemble, or fold, into their functional structures and what the functional implications of dynamics within the context of a folded protein are.…
Read moreNew Folding@home software in beta
The beta release of our new client software is going well. Thanks to everyone who has tried it out and given us feedback! If you haven’t already, you can download…
Read moreUnraveling the Mystery of Drug Specificity: The Case of Blebbistatin
When it comes to designing novel drugs, achieving specificity is a major challenge. An effective drug must bind tightly to its target protein while avoiding unwanted side effects that can…
Read more