Results of a kinase study published

The paper on the results of a kinase study conducted by Dr. Diwakar Shukla and his fellow researchers has been published. This kinase under investigation is c-src, which has been a major research interest of FAH since 2009. C-src is involved in the onset of numerous most feared human cancers, and is a key molecular target for therapeutic interventions. We discovered a unique drug-binding site on c-src, and binding drugs to it deters c-src’s full activation. We also captured c-src’s dynamic behaviors in unprecedented fine details via FAH simulations. This study has profound implications for increasing specificity of future anti-cancer drugs, thus could potentially reduce side effects associated with chemotherapy drastically. Please see this paper and these blog posts from March 23rd and 24th for more information.