Yes it can. Our client will automatically set this up by default. Folding@home was the very first distributed computing project to utilize these specialized chips for distributed computing or for molecular dynamics simulations. For certain types of calculations, we’ve seen GPUs give us a 20-30x speedup over their CPU-based counterparts. See the GPU and High Performance FAQs. We’ve heard a few reports that folding on GPUs can impact system performance, and we are currently working towards measures to resolve the issue.
