We have been able to fold several proteins into the 1.5 millisecond time range with experimental validation of our folding kinetics. This is a timescale a thousand times longer than any previous atomic-level simulation, and represents a fundamental advance over previous work. We are now simulating important proteins used in structural biology studies of folding as well as proteins involved in disease. We’ve been able to perform detailed simulations of many of these proteins at biologically-relevant timescales, giving us insights that had previously been unobtainable. We’ve also identified several potential drug candidates which may be able to fight Alzheimer’s, cancer, and infection by viruses. Peer-reviewed scientific papers detailing our results are posted on our Results page, and many of them are published in top journals such as Science, Nature, PNAS, and JMB. These publications are highly detailed and often technical, but summaries of their findings can be found on Results page as well as the Folding@home article on Wikipedia.
