In the early years of Folding@home we concentrated on developing new methods to tackle the computational challenges of simulating protein folding and applying these methods to gain new insights. In the last 5-7 years, we have been working on using these methods and insights to simulate Aß protein misfolding, a key process in the toxicity of Alzheimer’s Disease (AD). Our current goal is to use FAH for the development of new therapeutic strategies for AD. I feel that we are very much on track and we have seen some interesting results towards that goal.
